Groundbreaking research led by PhD student Orr Shahar, in collaboration with Dr. Alexander Botvinnik, has revealed promising results on the therapeutic use of psychedelic mushrooms.
The recently published study found that psilocybin-containing mushroom extract exhibits a more potent and long-lasting effect on synaptic plasticity compared to its synthetic counterpart. This discovery opens new perspectives in the treatment of psychiatric disorders, offering hope for those who do not respond to conventional treatments.
According to Dr. Fabiano de Abreu Agrela, Post PhD in Neuroscience and Master in Health Sciences in the areas of Psychology and Neuroscience, member of the Society for Neuroscience in the United States, “the research highlights the revolutionary potential of natural psychedelic compounds in neuroplasticity and treatment of mental illness.”
Key points of the study include:
1. Enhanced Neuroplasticity: Mushroom extract has demonstrated a stronger and more prolonged impact on synaptic plasticity, potentially offering unique therapeutic benefits.
2. Differences in Metabolic Profile: Metabolic analyzes revealed distinct metabolic profiles between mushroom extract and synthetic psilocybin, indicating the former’s unique influence on oxidative stress and energy production pathways.
3. Feasibility of Controlled Cultivation: Despite challenges in producing consistent natural extracts, controlled cultivation of mushrooms offers a promising approach to replicating extracts for medicinal use.
This discovery highlights the importance of continued research into natural psychedelic compounds and their therapeutic potential. As more studies are conducted, the hope is that new treatment options will emerge for those suffering from mental illnesses that are resistant to conventional treatments.
Dr. Fabiano de Abreu Agrela concluded: “As we explore new horizons in medicine, it is vital to consider innovative, nature-based approaches to addressing our society’s mental health challenges. This discovery is a significant step in the right direction.”
