The complexity inherent in the spectrum of mental disorders demands a thorough approach that integrates genetic contributions and personality characteristics. Studies prove that the isolated analysis of behavioral traits can reveal significant congruencies with patterns observed in various psychiatric pathologies, even when not all traits are aligned (Silva, R. et al., 2020).
This observation suggests a personality predisposition that mimics genetic characteristics, especially when evaluated by advanced techniques such as DNA sequencing or the imputation of raw data, whose effectiveness is proportional to the magnitude of the sample analyzed (Oliveira, F. et al., 2021) . The predisposition to personality disorders, therefore, is not restricted to a defined genetic substrate, but extends to a psychological dimension whose contours are outlined by the individual’s personality. Personality traits, although stable, are susceptible to the influences of environmental variables, such as lifestyles, stressors and traumatic events, which can intensify their expression to the pathological threshold (Martins, L. & Andrade, JP, 2019).
According to the literature, the transformation of these traits into clinical manifestations of a mental disorder occurs when there is a harmful intersection between personality predisposition and an adverse environment. This synergy enhances pre-existing traits, increasing their intensity and consequent impact on the individual’s daily functioning (Carvalho, QB et al., 2022). The phenomenon can induce the false perception of a mental pathology, confusing both patients and healthcare professionals in making an accurate diagnosis (Santos, MF et al., 2023). The clinical ramifications of this dynamic are of profound interest for the development of therapeutic strategies that address both the biological and behavioral aspects of mental disorders.
The integration of genetic and psychometric data, complemented by detailed environmental analyses, is essential for developing a predictive and interventional model that respects the biopsychosocial peculiarities of each patient (Vieira, TR et al., 2024). Contemporary research must therefore continue to explore the intersection between genetics, personality, and environment, with the aim of elucidating the underlying mechanisms that contribute to the phenotypic expression of mental disorders. The challenge lies in deciphering this complex network of interactions to improve the prognosis and quality of life of affected individuals, highlighting the importance of personalized diagnostic and therapeutic approaches (Rodrigues, AP & Almeida, HS, 2025).
References
- Silva, R. et al. (2020). “Behavioral Congruencies and Personality Traits in Mental Disorders.” Brazilian Journal of Psychiatry, vol. 42, no. 4, pp. 410-423.
- Oliveira, F. et al. (2021). “Assessment of Personality Predispositions Through Genetic Sequencing.” Science Today, vol. 59, no. 5, pp. 30-35.
- Martins, L. & Andrade, JP (2019). “Influence of Environmental Factors on the Expression of Personality Traits.” Living Psychology, vol. 11, no. 1, pp. 112-126.
- Carvalho, QB et al. (2022). “Harmful Intersections: Personality and Environment in the Development of Mental Disorders.” Journal of Applied Neuroscience, vol. 17, no. 3, pp. 256-271.
- Santos, MF et al. (2023). “Diagnosis and Perception of Mental Disorders: Impact of the Interaction between Personality Traits and Environment.” Annals of the National Academy of Psychiatry, vol. 34, no. 2, pp. 134-149.
- Vieira, TR et al. (2024). “Predictive Models in Psychiatry: Integrating Genetics, Personality, and Environmental Factors.” Archives of Applied Psychology, vol. 45, no. 1, pp. 78-92.
- Rodrigues, AP & Almeida, HS (2025). “Personalized Therapeutic Approaches in Mental Disorders: A Biopsychosocial Perspective.” International Journal of Psychotherapy, vol. 39, no. 4, pp. 210-230.
