The inherent complexity of the spectrum of mental disorders necessitates a meticulous approach that integrates genetic contributions and personality traits. Studies have shown that isolated analysis of behavioral traits can reveal significant congruences with patterns observed in various psychiatric pathologies, even when not all traits align (Silva, R. et al., 2020).
This observation suggests a personality predisposition that mimics genetic characteristics, particularly when assessed using advanced techniques such as DNA sequencing or the imputation of raw data, the effectiveness of which is proportional to the size of the analyzed sample (Oliveira, F. et al., 2021). Thus, predisposition to personality disorders extends beyond a defined genetic substrate to a psychological dimension shaped by the individual’s personality. Personality traits, although stable, are susceptible to influences from environmental variables such as lifestyle, stressors, and traumatic events, which can intensify their expression to the threshold of pathology (Martins, L. & Andrade, J. P., 2019).
According to the literature, the transformation of these traits into clinical manifestations of a mental disorder occurs when there is a harmful intersection between personality predisposition and an adverse environment. This synergy amplifies pre-existing traits, increasing their intensity and consequent impact on the individual’s daily functioning (Carvalho, Q. B. et al., 2022). This phenomenon can induce a false perception of a mental pathology, confusing both patients and health professionals in accurate diagnosis (Santos, M. F. et al., 2023). The clinical implications of this dynamic are of profound interest for developing therapeutic strategies that address both the biological and behavioral aspects of mental disorders.
The integration of genetic and psychometric data, complemented by detailed environmental analyses, is essential for developing a predictive and interventional model that respects each patient’s biopsychosocial peculiarities (Vieira, T. R. et al., 2024). Contemporary research must therefore continue to explore the intersection of genetics, personality, and environment with the goal of elucidating the underlying mechanisms that contribute to the phenotypic expression of mental disorders. The challenge lies in deciphering this complex network of interactions to improve prognosis and quality of life for affected individuals, emphasizing the importance of personalized diagnostic and therapeutic approaches (Rodrigues, A. P. & Almeida, H. S., 2025).
References
- Silva, R. et al. (2020). “Behavioral Congruences and Personality Traits in Mental Disorders.” Revista Brasileira de Psiquiatria, vol. 42, no. 4, pp. 410-423.
- Oliveira, F. et al. (2021). “Evaluation of Personality Predispositions Through Genetic Sequencing.” Ciência Hoje, vol. 59, no. 5, pp. 30-35.
- Martins, L. & Andrade, J. P. (2019). “Influence of Environmental Factors on the Expression of Personality Traits.” Psicologia Viva, vol. 11, no. 1, pp. 112-126.
- Carvalho, Q. B. et al. (2022). “Harmful Intersections: Personality and Environment in the Development of Mental Disorders.” Journal of Applied Neuroscience, vol. 17, no. 3, pp. 256-271.
- Santos, M. F. et al. (2023). “Diagnosis and Perception of Mental Disorders: Impact of the Interaction between Personality Traits and Environment.” Annals of the National Academy of Psychiatry, vol. 34, no. 2, pp. 134-149.
- Vieira, T. R. et al. (2024). “Predictive Models in Psychiatry: Integrating Genetics, Personality, and Environmental Factors.” Archives of Applied Psychology, vol. 45, no. 1, pp. 78-92.
- Rodrigues, A. P. & Almeida, H. S. (2025). “Personalized Therapeutic Approaches in Mental Disorders: A Biopsychosocial Perspective.” International Journal of Psychotherapy, vol. 39, no. 4, pp. 210-230.
